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Fluidx Medical’s GPX liquid embolic device
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Controllable. Versatile. Simple.

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GPX Embolic Device is an innovative embolic agent that is designed for ease of use, versatility, and improved control during delivery.

  • Simple preparation (ready-to-use syringe, no special materials or catheters required)

  • Controllable material delivery

  • Radiopaque material allows for real-time visualization

  • Occlusion is not based on a patient’s coagulation situation 

  • Deep penetration into vessel beds

  • Durable occlusion

Hip Skele Xray

Clinical Need

Embolic devices are widely used to stop blood flow for targeted treatment of hypervascular tumors, vessel malformations, internal bleeds, and other cancer-related uses.

Some challenges that clinicians may experience with embolic devices today include:

Complicated and lengthy preparation process with special materials and delivery catheters often required

Lack of complete penetration of the vessel beds and tumor feeding vessels

Device control challenges and lack of real-time visibility during delivery which may result in less effective use and potential damage to healthy tissue

Reliance on a patient’s ability to coagulate blood flow, which can be limited in many very sick patients 

Technology

Fluidx Medical’s GPX embolization material

Innovative Embolic Technology

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  • Aqueous-based, low viscosity polymer solution in the delivery syringe

  • Ready-to-use, requires less than 1 minute of tableside preparation by the clinician

  • Can be delivered using standard microcatheters and no special solutions required

  • Solidifies rapidly upon delivery through an electrostatic mechanism of action without polymerization or dimethyl sulfoxide (DMSO) precipitation associated with other liquid embolics

  • Polymers bind upon delivery forming a durable, gel-like solid 

Innovative GPX Embolic technology requires no DMSO and minimal preparation

GPX Delivery

Deployment of GPX in a portal vein segment

GPX liquid embolic used for portal vein embolization

GPX-Clear Embolic Device*

The GPX-Clear Embolic Device leverages the core GPX technology as well as incorporates a non-artifact inducing radiopacity agent.  The radiopacity agent then dissipates within 24 hours post-delivery, enabling unobstructed visibility of the treated area.

Pretreatment angiogram

Pretreatment angiogram

Fluoroscopic 1-day Post embolization

Fluoroscopic image 1-day post-embolization showing dissipation of radiopacity

Fluoroscopic showing GPX-Clear Placement

Fluoroscopic image taken immediately after delivery showing GPX-Clear Embolic Device placement

Post-treatment DSA

Post-treatment DSA showing complete occlusion of targeted region with    GPX-Clear Embolic Device

Radiopacity 1-hr post-GPX-Clear

Radiopacity 1-hr post-GPX-Clear Embolic Device delivery

Radiopacity 24-hr post-GPX-Clear

Radiopacity dissipated at 24-hr post-GPX-Clear Embolic Device delivery 

* Data on file. Fluidx Medical Technology.

† Based on in vivo study. Data on file. Fluidx Medical Technology. In vivo results are not necessarily indicative of clinical results.

‡ Early clinical case studies. Data on file. Fluidx Medical Technology.

The GPX Embolic Device is under development and does not have marketing clearance or approval in any market at this time.  For investigational use (in New Zealand) only.

The GPX-Clear Embolic Device is under development and does not have marketing clearance or approval in any market at this time.