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GPX Embolic Device*

GPX Embolic Device is an innovative embolic agent that is designed for ease of use, versatility, and improved control during vascular embolization.

  

The GPX technology is a low viscosity, aqueous-based solution in a syringe that solidifies into a durable embolic material upon delivery, without polymerization or dimethyl-sulfoxide (DMSO) precipitation associated with other embolics.

GPX is packaged ready-to-use in a syringe, requires less than 2 minutes of tableside preparation by the clinician, and may be delivered through standard catheters or microcatheters.    

 

Why GPX?

The GPX Embolic Device is an innovative embolic designed to combine the benefits of other embolics like coils, particles, and liquids with simple preparation, delivery, precision, and control leading to durable, long-term occlusions.*


Therapeutic, super-selective embolization is a high-growth procedure used for minimally invasive, targeted treatment of internal bleeds, tumors, aneurysms, vascular malformations, uterine fibroids, varicose veins, and other uses. Millions of embolization devices are used each year for these types of procedures across peripheral vascular, interventional oncology, and neurovascular applications.


Embolic devices today can be difficult to use and lack controllability and precision in delivery.  Particles and microspheres are useful embolics across a variety of applications, however they can be difficult to control, typically are not radiopaque, and do not allow the clinician to create a targeted plug.  Metallic coils can create a plug to occlude flow, but can be unpredictable during delivery and often require numerous, expensive deployments to achieve the desired occlusion. Liquid embolics have advantages for certain targeted procedures, but require special materials and delivery techniques, and use can result in accidental catheter entrapment in the body.

 

Tumor Devascularization**

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Baseline angiogram

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Angiogram post-GPX delivery through microcatheter

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DSA post-GPX delivery

 

Portal Vein Embolization**

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Baseline angiogram

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Angiogram post-GPX delivery through microcatheter

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DSA post-GPX delivery

 

Interventional Oncology Use**

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Baseline angiogram

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DSA post-GPX delivery

 

Super-Selective Embolization**

Pre-placement Angiogram

Baseline angiogram

Angiogram post-GPX injection through microcatheter.

Angiogram post-GPX delivery through microcatheter

Angiogram post-GPX injection selected sites

Angiogram post-GPX delivery selected sites

 

Effective Distal Penetration**

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GPX in Kidney - Demonstrating Distal Penetration

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GPX in Kidney (magnified)